Since the arrival of the first vaccines against SARS-CoV-2 virus the nature of serological tests supporting the COVID-19 emergency has changed. At first the aim was to track down the spread of the virus among the population. However, over time it has become increasingly important to support the ongoing vaccination campaigns.
GENmonitor™ COVID-19 NEUTRALISING Ab RAPID TEST is a rapid device for the qualitative detection of IgG antibodies against the SARS-CoV-2 Spike protein in human serum, blood, and plasma samples.
One of the most important proteins involved in the virus infection process is the Spike protein, which covers the whole virus’ surface. It is divided into two portions: one contains a region known as RBD (Receptor Binding Domain) which allows the virus to bind to the host cell by adhering to the ACE2 receptor; while the other allows the virus to enter the cell subsequently. This evidence allows to assume that an antibody capable of inhibiting the interaction between the Spike protein and the ACE2 receptor would potentially prevent coronavirus infection and the associated disease.